Most painters and paperhangers work 40 hours a week or less; about one-fourth have variable schedules or work part time. Painters and paperhangers must stand for long periods, often working from scaffolding and ladders. Their jobs also require a considerable amount of climbing and bending. These workers must have stamina, because much of the work is done with their arms raised overhead. Painters often work outdoors but seldom in wet, cold, or inclement weather. Some painting jobs can leave a worker covered with paint.

Painters and paperhangers sometimes work with materials that are hazardous or toxic, such as when they are required to remove lead-based paints.